American College Of Surgeons - Inspiring Quality: Highest Standards, Better Outcomes

ACS Clinical Research Program Committees

The American College of Surgeons Clinical Research Program (ACS CRP) maintains one administrative committee (Education) and three scientific committees (Cancer Care Delivery Research, Cancer Care Standards Development, and Dissemination & Implementation).

Education Committee

Goals

  • Increase knowledge and awareness of ongoing clinical trials
  • Increase knowledge and awareness of new evidence (clinical trial results) and practice standards
  • Reduce the time from trials reporting to practice implementation

Current Educational Programs

Upcoming Investigator Webinar

CRP Investigator Webinar: Breast (NRG BR005, A221505 [RT-CHARM])
Thursday, October 11, 2018 4:00-5:00pm CT
Moderator: Judy C. Boughey, MD, FACS Education Committee, ACS CRP
Speakers: Terry Mamounas, MD, MPH, FACS, Matthew Poppe, MD, Jamie Wagner, DO, FACOS

ACS CRP Sessions at Clinical Congress 2018

ME112: Caring for the Young Adult Cancer Patient
Monday, October 22, 1:15-2:15pm ET
Moderators: Clancy Clark, Y. Nancy You

PS319: Surgical Emergencies in the Cancer Patient
Wednesday, October 24, 12:45-2:15pm ET
Moderators: Martin Weiser, Brian Badgwell

2018 ACS CRP Articles from the Bulletin of the American College of Surgeons

January 2018: Francescatti AB, You YN, Boughey JC. Clinical trials for surgeons: Hurdles and opportunities. Bull Am Coll Surg. 103(1).

February 2018: Dickson-Witmer D, Degnim AC, Bedrosian I, Boughey JC. Surgical management of ADH, ALH, and LCIS. Bull Am Coll Surg. 103(2).

March 2018: Francescatti AB, A. Finlayson EV, MD, MS, FACS, Dohan D., Chang GJ. Improving surgical care and outcomes through the OPTI-Surg toolkit. Bull Am Coll Surg. 103(3).

April 2018: Smoot RL, Rocha FG, Boughey JC. Adjuvant therapies for biliary tract cancers. Bull Am Coll Surg. 103(4).

May 2018: Meyerhardt JA, Boughey JC, You Y. Duration of adjuvant therapy for stage III colon cancer: No longer one size fits all. Bull Am Coll Surg. 103(5).

June 2018: Soares KC, Roland CL, Boughey JC. Immunotherapy in Solid Tumor. Bull Am Coll Surg. 103(6).

July 2018: Clark CJ, Guerard E, Boughey JC. Geriatric Assessment and Frailty in Older Cancer Patients. Bull Am Coll Surg. 103(7).

August 2018: Rocha FG, Boughey JC. Liquid biopsies in cancer clinical trials. Bull Am Coll Surg. 103(8).

ACS CRP Honorary Lecturers

Lawrence Shulman, MD, FACP: Phase III Randomized Clinical Trials, Pragmatic Trials, and Big Data: What is the future? (Alliance Group Meeting November 2018)

Kelly Hunt, MD, FACS: How co-operative group clinical trials have shaped the surgical management of breast cancer (Alliance Group Meeting November 2016)

Heidi Nelson, MD, FACS: The future of surgical research within the changing landscape of research funding (Alliance Group Meeting November 2015)

Clifford Ko MD, MS, MSHS, FACS: Surgical quality management and outcomes in oncologic care (Alliance Group Meeting May 2015)

Elaine Mardis, PhD: Information from genomic analysis from Z1031 and beyond (Alliance Group Meeting November 2014)

Resources

Alliance for Clinical Trials in Oncology

Open Clinical Trials through the Alliance for Clinical Trials in Oncology

Alliance Membership Application

ClinicalTrials.gov

Dissemination & Implementation Committee

Goals

  • Develop strategies for disseminating key cancer clinical trial results as well as design implementation research programs for cancer guidelines
  • Collaborate with the Commission on Cancer and components of the ACoS and the Alliance to disseminate and implement standards based on new information from clinical trials
  • Investigate novel ways to hasten and broaden uptake in clinical practice of changes indicated by results of clinical trials

Cancer Care Standards Development Committee

Goals

  • Promote prompt dissemination and adoption of clinical trials results by all practitioners involved in cancer care
  • Provide a focus for research to determine the impact of clinical decision support tools on cancer treatment outcomes
  • Ensure optimal research quality by review of the surgical components of Alliance protocols

Accomplishments

Operative Standards for Cancer Surgery Volume I: Breast, Lung, Pancreas, Colon

Operative Standards for Cancer Surgery Volume II: Esophagus, Gastric, Melanoma, Rectum, Thyroid
(forthcoming August 24, 2018)

Cancer Care Delivery Research Committee

Goal

Improve cancer care outcomes through high-quality health services that leverage the multidisciplinary collaboration and research infrastructure of the ALLIANCE, NCI Community Oncology Research Program (NCORP), and other partners to generate new knowledge and facilitate the implementation and dissemination of research findings throughout the oncology community.

Major Research Priority Areas

Some areas include:

  • Patient/Caregiver Communication
  • Clinical Care Coordination
  • Impact of Financial Burden of Care
  • Health Care Systems
  • Quality of Care
  • Impact of Precision Medicine

The committee has developed studies in patient-centered outcomes and clinical comparative effectiveness research, cancer economics, and systems redesign. We continue to develop studies to be conducted both within the NCORP Cancer Care Delivery Research (CCDR) program and also through the Alliance Foundation and the Commission on Cancer. Current concepts focus on post-treatment surveillance after cancer treatment, decision support, implementation of tools into practice, and cost effectiveness of treatments.

Resources

Cancer Care Delivery Research: Building the Evidence Base to Support Practice Change in Community Oncology (Kent et al.)

Alliance Cancer Care Delivery Research Pilot Project Awards

NCI Community Oncology Research Program (NCORP)

Active NCORP Studies

A191402CD: Testing decision aids to improve prostate cancer decisions for minority men
PI: Jon Tilburt, MD, MPH

NCORP Protocols in Development

A231601CD: Improving surgical care and outcomes in older cancer patients through implementation of an efficient pre-surgical toolkit (OPTI-Surg)
PIs: George Chang, MD, MS; Emily Finlayson, MD, MS

A231602CD: Assessing financial toxicity in patients with blood cancers
PI: Rena Conti, PhD

A231701CD: Increasing socioeconomically disadvantaged patients’ engagement in breast cancer surgery decision making through a shared decision making intervention
PI: Heather Neuman, MD

Alliance Foundation Trials (AFT) CCDR Protocols

AFT 25: Comparison of operative to monitoring and endocrine therapy for low risk DCIS: The COMET trial
PI: Shelley Hwang, MD, MPH

AFT 28: CANVAS randomized trial comparing direct oral anticoagulants to low molecular weigh heparin +/- warfarin for VTE in cancer
PI: Deborah Schrag, MD, MPH

AFT 39: Electronic patient reporting of symptoms during outpatient cancer treatment: A U.S. national randomized controlled trial (PRO-TECT)
PI: Ethan Basch, MD, MSc

Contact Us

For more information on the ACS CRP committees or to inquire about participation, please e-mail clinicalresearchprogram@facs.org.