American College Of Surgeons - Inspiring Quality: Highest Standards, Better Outcomes

ACS Cancer Research Program Committees

The American College of Surgeons Cancer Research Program (ACS CRP) maintains one administrative committee (Education) and three scientific committees (Cancer Care Delivery Research, Cancer Care Standards Development, and Dissemination & Implementation).

Education Committee

Chair: Judy C. Boughey, MBBCh, FACS

Vice-Chair: Rebecca A. Snyder, MD, MPH, FACS


  • Increase knowledge and awareness of ongoing clinical trials
  • Increase knowledge and awareness of new evidence (clinical trial results) and practice standards
  • Reduce the time from trials reporting to practice implementation

ACS CRP Articles from the Bulletin of the American College of Surgeons

The Bulletin of the American College of Surgeons is the College’s monthly member magazine, containing articles on topics that affect surgical practice and the surgical profession. Each month, the ACS CRP publishes an article in the Bulletin related to clinical trials in cancer.

Read the latest ACS CRP column

ACS CRP Honorary Lecturers at the Alliance for Clinical Trials in Oncology Group Meetings

Ronald P. DeMatteo, MD, FACS: Rapid adoption of tyrosine kinase inhibitors in GIST through clinical trials (Alliance Group Meeting November 2019)

Lawrence Shulman, MD, FACP: Phase III Randomized Clinical Trials, Pragmatic Trials, and Big Data: What is the future? (Alliance Group Meeting November 2018)

Kelly Hunt, MD, FACS: How co-operative group clinical trials have shaped the surgical management of breast cancer (Alliance Group Meeting November 2016)

Heidi Nelson, MD, FACS: The future of surgical research within the changing landscape of research funding (Alliance Group Meeting November 2015)

Clifford Ko MD, MS, MSHS, FACS: Surgical quality management and outcomes in oncologic care (Alliance Group Meeting May 2015)

Elaine Mardis, PhD: Information from genomic analysis from Z1031 and beyond (Alliance Group Meeting November 2014)

Dissemination & Implementation Committee

Co-Chairs: Sarah L. Blair, MD, FACS, and Sarah Birken, PhD

Vice-Chair: Diana Dickson-Witmer, MD, FACS


  • Develop strategies for disseminating key cancer clinical trial results as well as design implementation research programs for cancer guidelines
  • Collaborate with the Commission on Cancer and components of the ACoS and the Alliance to disseminate and implement standards based on new information from clinical trials
  • Investigate novel ways to hasten and broaden uptake in clinical practice of changes indicated by results of clinical trials

Cancer Care Standards Development Committee

Chair: Christina L. Roland, MD, MS, FACS

Vice-Chair: Nirmal K. Veeramachaneni, MD, FACS


  • Promote prompt dissemination and adoption of clinical trials results by all practitioners involved in cancer care
  • Provide a focus for research to determine the impact of clinical decision support tools on cancer treatment outcomes
  • Ensure optimal research quality by review of the surgical components of Alliance protocols

Cancer Care Delivery Research Committee

Co-Chairs: George J. Chang, MD, MS, FACS, and Heather B. Neuman, MD, MS, FACS

Vice-Chair: Stephen B. Edge, MD, FACS


Improve cancer care outcomes through high-quality health services that leverage the multidisciplinary collaboration and research infrastructure of the Alliance for clinical Trials in Oncology, NCI Community Oncology Research Program (NCORP), and other partners to generate new knowledge and facilitate the implementation and dissemination of research findings throughout the oncology community.

Active NCORP CCDR Protocols

Study participation for the following NCORP protocols is limited to NCORP institutions only.

A231601CD: Improving surgical care and outcomes in older cancer patients through implementation of an efficient pre-surgical toolkit (OPTI-Surg)
PIs: George Chang, MD, MS; Emily Finlayson, MD, MS

This Alliance trial looks at how well the use of a pre-surgical toolkit (OPTI-Surg) works in improving surgical care and outcomes in older participants with cancer. In many elderly patients, surgery can greatly affect physical condition and the ability to return to pre-surgery levels of physical functioning. Providing pre-surgical recommendations may help improve participants' recovery rate and functioning after surgery.

A231602CD: Assessing financial toxicity in patients with blood cancers
PI: Rena Conti, PhD

This trial studies financial difficulty in participants with chronic lymphocytic leukemia and multiple myeloma. Assessment of financial difficulty may help to better understand the financial impact of cancer and come up with ways to help participants avoid financial problems during treatment.

This trial is temporarily suspended to new patient registration.

A231701CD: Increasing socioeconomically disadvantaged patients’ engagement in breast cancer surgery decision making through a shared decision making intervention
PI: Heather Neuman, MD

This limited access Alliance trial looks at how well a breast cancer surgery decision aid works in increasing patient engagement in decision making for patients with newly diagnosed stage 0-III breast cancer. The trial also examines barriers to patient engagement even with the use of a decision aid, and if barriers are more likely to be experienced by patients who are socioeconomically disadvantaged.

Alliance Foundation Trials (AFT) CCDR Protocols

AFT 25: Comparison of operative to monitoring and endocrine therapy for low risk DCIS: The COMET trial
PI: Shelley Hwang, MD, MPH

This study looks at the risks and benefits of active surveillance (AS) compared to guideline concordant care (GCC) in the setting of a pragmatic prospective randomized trial for low risk DCIS. The overarching hypothesis is that management of low-risk Ductal Carcinoma in Situ (DCIS) using an AS approach does not yield inferior cancer or quality of life outcomes compared to GCC.

This trial is currently recruiting participants.

AFT 28: CANVAS randomized trial comparing direct oral anticoagulants to low molecular weigh heparin +/- warfarin for VTE in cancer
PI: Deborah Schrag, MD, MPH

The overarching objective of this study is to determine the effectiveness of LMWH/warfarin vs. DOAC anticoagulation for preventing recurrent VTE in cancer patients. The intervention strategy is Direct Oral AntiCoagulants (DOAC) therapy with edoxaban, apixaban, rivaroxaban, or dabigatran. The comparator is low molecular weight heparin (LMWH) alone or with warfarin. The information gained will empower cancer patients and physicians to make more informed choices about anticoagulation strategies to manage VTE.

This trial is currently recruiting participants.

AFT 39: Electronic patient reporting of symptoms during outpatient cancer treatment: A U.S. national randomized controlled trial (PRO-TECT)
PI: Ethan Basch, MD, MSc

This study is designed to test nationally whether patients’ outcomes and utilization of services can be improved through symptom monitoring via patient-reported outcomes between visits.

This trial is currently recruiting participants.

Contact Us

For more information on the ACS CRP committees or to inquire about participation, please e-mail