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ACS Brief

Laparoscopic Resection Rectopexy Is Superior to Delorme’s Procedure for Rectal Prolapse

April 22, 2025

Herrle F, Sandra-Petrescu F, Rothenhoefer S, et al. Laparoscopic Resection Rectopexy Versus Delorme's Procedure In Full-Thickness Rectal Prolapse—A Randomized Multicenter Trial (DELORES-RCT). Ann Surg. 2025; in press.

The DELORES randomized trial compared outcomes of laparoscopic resection rectopexy (LRR) with the Delorme procedure (DP) for treatment of full-thickness rectal prolapse. Patients (n = 65) were randomized LRR or DP, and the main outcomes of interest were recurrence rates at 2 years after surgery. Quality of life (QOL), constipation, and fecal incontinence were also assessed.

The data analysis showed that recurrence was documented in 8.2% of the LRR group and 42.8% of the DP group. Most recurrences were observed in the first postoperative year. Standard QOP assessments showed that QOL was significantly better in the LRR group. Fecal incontinence was graded according to the Wexner scoring system, and scores were more favorable in the LRR group.

The authors concluded that LRR was superior to DP and should be the preferred approach for management of rectal prolapse.

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