American College Of Surgeons - Inspiring Quality: Highest Standards, Better Outcomes

V39N7: Nutrition and Metabolic Disease

Recommended Reading

Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med. 2011;365(6):506-517. Free full text

Casaer and colleagues report a randomized trial comparing early versus late parenteral nutrition in critically ill patients. The trial showed no advantage for early parenteral nutrition.

Dickerson RN, Pitts SL, Maish GO 3rd, et al. A reappraisal of nitrogen requirements for patients with critical illness and trauma. J Trauma Acute Care Surg. 2012;73(3):549-557.

This report describes a study designed to measure nitrogen requirements in injured patients. The results show that conventional predicted nitrogen requirements underestimate need, particularly in patients with traumatic brain injury.

Dorman RB, Serrot FJ, Miller CJ, et al. Case-matched outcomes in bariatric surgery for treatment of type 2 diabetes in the morbidly obese patient. Ann Surg. 2012;255(2):287-293.

This report presents data that confirm the short-term effectiveness of bariatric procedures for the treatment of type 2 diabetes in morbidly obese patients.

Gianotti L, Braga M, Biffi R, et al. Perioperative intravenous glutamine supplementation in major abdominal surgery for cancer: a randomized multicenter trial. Ann Surg. 2009;250(5):684-690.

Gianotti and associates report a trial of glutamine-supplemented intravenous nutrition in well-nourished surgical patients. The trial showed no benefit from glutamine supplementation.

Heyland D, Muscedere J, Wischmeyer PE, et al. A randomized trial of glutamine and antioxidants in critically ill patients. N Engl J Med. 2013;368(16):1489-1497.

This article reports a randomized trial of supplemental glutamine and antioxidants in critically ill patients. The results showed increased mortality in patients receiving supplemented nutrition. No improvement in any outcome measure was observed.

Hur H, Kim SG, Shim JH, et al. Effect of early oral feeding after gastric cancer surgery: a result of randomized clinical trial. Surgery. 2011;149(4):561-568.

This trial showed that early oral feeding after gastrectomy was safe and associated with earlier hospital discharge.

Johnson BL, Blackhurst DW, Latham BB, et al. Bariatric surgery is associated with a reduction in major macrovascular and microvascular complications in moderately to severely obese patients with type 2 diabetes mellitus. J Am Coll Surg. 2013;216(4):545-556; discussion 556-558.

This report of data from a large, state medical database showed a reduction of macrovascular and microvascular complications in patients with type 2 diabetes treated with bariatric surgical procedures.

Koopmann MC, Kudsk KA, Szotkowski MJ, et al. A team-based protocol and electromagnetic technology eliminate feeding tube placement complications. Ann Surg. 2011;253(2):287-302.

This report confirms the safety and success of team-based feeding tube insertion using electromagnetic placement assistance devices.

Mingrone G, Panunzi S, De Gaetano A, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med. 2012;366(17):1577-1585. Free full text

This article describes a randomized trial comparing bariatric surgery and medical therapy for type 2 diabetes. Over the short term, bariatric surgery produced superior results in obese patients.

Sigalet D, Boctor D, Brindle M, et al. Elements of successful intestinal rehabilitation. J Pediatr Surg. 2011;46(1):150-156.

Sigalet and colleagues describe a protocol-based approach to intestinal rehabilitation in children. The protocol resulted in earlier weaning from parenteral nutrition compared with historical control data.

Williams FN, Jeschke MG, Chinkes DL, et al. Modulation of the hypermetabolic response to trauma: temperature, nutrition, and drugs. J Am Coll Surg. 2009;208(4):489-502. Free full text

This report reviews data on efforts to modulate the metabolic response to burn injury in children.