American College Of Surgeons - Inspiring Quality: Highest Standards, Better Outcomes

V38N2: Spleen

Cadili A, de Gara C. Complications of splenectomy. Am J Med. 2008;121(5):371-5.

This article presents a clear and concise review of the known and suspected complications of splenectomy.

Di Sabatino A, Carsetti R, Corazza GR. Post-splenectomy and hyposplenic states. Lancet. 2011;378(9785):86-97.

This article provides detailed information on the pathophysiology, diagnosis, and management of asplenia and the hyposplenic states.

Grikscheit TC, Sala FG, Ogilvie J, et al. Tissue-engineered spleen protects against overwhelming pneumococcal sepsis in a rodent model. J Surg Res. 2008;149(2):214-8.

This is an interesting description of experimental work documenting that a tissue-engineered spleen provides protection against postsplenectomy infection in a rodent model.

Harbrecht BG, Ko SH, Watson GA, et al. Angiography for blunt splenic trauma does not improve the success rate of nonoperative management. J Trauma. 2007;63(1):44-9.

This article reviews experience from a large Level 1 trauma center. The use of angioembolization did not improve the rate of successful nonoperative therapy for splenic injury this clinical series.

Katz SC, Pachter HL. Indications for splenectomy. Am Surg. 2006;72(7):565-80.

This article is a clear and helpful review of the indications for splenectomy.

Lakin RO, Bena JF, Sarac TP, et al. The contemporary management of splenic artery aneurysms. J Vasc Surg. 2011;53(4):958-64; discussion 965.

This article reviews experience with the diagnosis and management of splenic artery aneurysms.

Perrotta S, Gallagher PG, Mohandas N. Hereditary spherocytosis. Lancet. 2008;372(9647):1411-1426.

This is a helpful review of the etiology, pathophysiology, diagnosis, and modern management of hereditary spherocytosis.

Pomp A, Gagner M, Salky B, et al. Laparoscopic splenectomy: a selected retrospective review. Surg Laparosc Endosc Percutan Tech. 2005;15(3):139-43.

This article provides a review of a sizeable clinical experience with laparoscopic splenectomy.

Renzulli P, Hostettler A, Schoepfer AM, et al. Systematic review of atraumatic splenic rupture. Br J Surg. 2009;96(10):1114-21.

This review of the literature on atraumatic spleen rupture provides a helpful overview of this topic.

Requarth JA, D'Agostino RB, Jr., Miller PR. Nonoperative management of adult blunt splenic injury with and without splenic artery embolotherapy: a meta-analysis. J Trauma. 2011;71(4):898-903; discussion 903.

This article provides a large database analysis of the value of angioembolization as an adjunct to the nonoperative management of splenic injury. Unfortunately, the recommendation that angioembolization is valuable is not strongly supported by the data presented.

Richardson JD. Changes in the management of injuries to the liver and spleen. J Am Coll Surg. 2005;200(5):648-69.

This is a helpful overview of the management of spleen injury presented by an experienced trauma surgeon.

Schwartz RS. Immune thrombocytopenic purpura—from agony to agonist. N Engl J Med. 2007;357(22):2299-301.

This is a useful review of the pathogenesis and pathophysiology of ITP.

Skandalakis PN, Colborn GL, Skandalakis LJ, et al. The surgical anatomy of the spleen. Surg Clin North Am. 1993;73(4):747-68.

This classic article provides a detailed description of the surgical anatomy of the spleen.