American College Of Surgeons - Inspiring Quality: Highest Standards, Better Outcomes

Statins boost traumatic brain injury survival rate

OCTOBER 24. 2017
Clinical Congress Daily Highlights, Tuesday Second Edition 

Patients who experience traumatic brain injury (TBI) while on statins live longer than those not on the drugs, a new study finds. The results are consistent with those seen in animal models, but the authors caution that further research is necessary to evaluate the potential of statins as a therapeutic drug for TBI.

Researchers led by Adil Lokhandwala, MD, University of Arizona, Tucson, AZ, examined records of 980 TBI patients 40 years and older in the Multiparameter Intelligent Intensive Care Monitoring (MIMIC) III database who stayed more than 24 hours in the intensive care unit (ICU). Patients on statins had an 88 percent hospital survival rate, compared with 68.4 percent in the non-statin group. After controlling for confounding factors, the odds ratio of survival for patients on statins was 1.8. There were no significant differences in hospital or ICU length of stay between two groups.

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This Scientific Forum presentation was delivered October 24 at the 2017 Clinical Congress of the American College of Surgeons in San Diego, CA.  Program, webcast and audio information is available online at

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